Domains of Structured Oral Anticancer Medication Programs: A Scoping Review.
Domains of Structured Oral Anticancer Medication Programs: A Scoping Review.
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DOI：
10.1188/22.onf.296-306
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发表时间：
2022-06-17
影响因子：
1.9
通讯作者：
Morgan, Rebecca L.
中科院分区：
文献类型：
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作者：
Sivakumaran, Kapeena;Ginex, Pamela K.;Waseem, Haya;Belcher, Sarah M.;Lagler-Clark, Sarah;LeFebvre, Kristine B.;Palmer, Nicole;Pasumarthi, Tejanth;Morgan, Rebecca L.
为了支持患者坚持口服抗癌药物(OAM)的多因素过程，跨专业的方法是必要的。这一范围审查旨在确定已发表文献中的结构化OAM计划，确定研究中的组成部分，并为机构开发或维护OAM计划提出一个框架。检索EMBASE®、PubMed®和CINAHL®数据库，检索2000年1月至2021年4月发表的研究。两位评价者筛选了研究并提取了数据。捕获了OAM程序的特征和特定领域。确定了方案的关键组成部分，并创建了指导方案开发的框架。在这21项研究中确定的组成部分包括教育、咨询、随访、专职临床医生联系、不良事件和毒性监测、依从性监测、药品采购、交付和供应、患者和系统层面的成本降低、信息技术和风险评估。基于研究结果，提出了建立和评估OAM遵守计划的框架。未来的研究应该评估这一框架的可靠性和有效性，因为进一步的测试可能会导致开发更多的组件。
An interprofessional approach is necessary to support the multifactorial process of patient adherence to oral anticancer medications (OAMs). This scoping review aims to identify structured OAM programs in published literature, identify components within studies, and propose a framework for institutions developing or maintaining OAM programs. Embase®, PubMed®, and CINAHL® databases were searched for studies published between January 2000 and April 2021. Two reviewers screened studies and extracted data. Characteristics and specific domains of the OAM programs were captured. Key components of the programs were identified, and a framework was created to guide program development. Components identified among the 21 studies were education; counseling; follow-up; dedicated clinician contact; adverse event and toxicity monitoring; adherence monitoring; drug procurement, delivery, and supply; patient- and system-level cost reduction; information technology; and risk assessment. Based on the findings, a framework for building and evaluating OAM adherence programs is proposed. Future studies should evaluate the reliability and validity of this framework because further testing may lead to the development of additional components.