ENZYMES AS RNA-BINDING PROTEINS - A ROLE FOR (DI)NUCLEOTIDE-BINDING DOMAINS
ENZYMES AS RNA-BINDING PROTEINS - A ROLE FOR (DI)NUCLEOTIDE-BINDING DOMAINS
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DOI：
10.1016/0968-0004(94)90198-8
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发表时间：
1994-03-01
影响因子：
13.8
通讯作者：
HENTZE, MW
中科院分区：
文献类型：
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作者：
HENTZE, MW
调节蛋白通常通过基序与DNA结合，这些基序被用来将这些蛋白归类为DNA结合蛋白家族。人们对RNA介导的基因调控的兴趣越来越大，导致RNA结合蛋白的不同基序也被发现，在最近的综述中，区分了10个‘RNP(核糖核蛋白)家族’，包括相对常见的RNP基序2、RGG盒2和Yd-I基序3。最近的发现表明，RNA结合基序的列表可能很快会有一个令人惊讶的新成员。
Regulatory proteins often bind to DNA via motifs that are used to classify these proteins into families of DNA-binding proteins. The increasing interest in RNA-mediated gene regulation has resulted in distinct motifs also being identified for RNA-binding proteins, in a recent review, ten'RNP (ribonucleoprotein) families' were distinguished], including the relatively common RNP motif 2, the RGG box 2 and the Yd-i motif 3. Recent findings suggest that the list of RNA-binding motifs could soon be extended by a surprising new member.