Retinal blood flow indices in patients infected with human immunodeficiency virus.
Retinal blood flow indices in patients infected with human immunodeficiency virus.
复制标题
人类免疫缺陷病毒感染患者的视网膜血流指数。
DOI：
10.1136/bjo.80.8.723
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Wolf,S
中科院分区：
文献类型：
--
作者：
Yung,CW;Harris,A;Massicotte,S;Chioran,G;Krombach,G;Danis,R;Wolf,S
目的/背景异常血流动力学被认为与人类免疫缺陷病毒（HIV）感染患者视网膜微血管疾病的发展有关。本研究采用扫描激光检眼镜（SLO）结合荧光素血管造影技术测量HIV血清阳性患者的视网膜血流指标。方法采用SLO荧光素血管造影检测23例HIV感染者和23例对照者的经静脉通过时间（AVP）和脐周毛细血管血流速度（CFV）。结果两组AVP差异无统计学意义。然而，CFV在HIV感染患者中显著降低（p = 0.013）。结论HIV感染患者在表皮包皮周毛细血管水平表现出异常的血流动力学。
AIMS/BACKGROUNDAbnormal blood flow dynamics are believed to contribute to the development of retinal microvascular disease in patients infected with human immunodeficiency virus (HIV). In this study, the scanning laser ophthalmoscope (SLO) was used, combined with fluorescein angiography, to measure retinal blood flow indices in HIV seropositive patients.METHODSArteriovenous passage time (AVP) and perifoveal capillary blood flow velocity (CFV) were measured in 23 HIV infected patients and 23 control subjects with SLO fluorescein angiography.RESULTSNo significant difference in AVP was found between the two groups. However, CFV was significantly reduced in HIV infected patients (p = 0.013).CONCLUSIONPatients infected with HIV show abnormal haemodynamics at the level of the perifoveal capillaries.