Visualization of Cerebrospinal Fluid Movement with Spin Labeling at MR Imaging: Preliminary Results in Normal and Pathophysiologic Conditions
Visualization of Cerebrospinal Fluid Movement with Spin Labeling at MR Imaging: Preliminary Results in Normal and Pathophysiologic Conditions
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DOI：
10.1148/radiol.2492071985
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发表时间：
2008-11-01
期刊：
影响因子：
19.7
通讯作者：
McComb, J. Gordon
中科院分区：
文献类型：
--
作者：
Yamada, Shinya;Miyazaki, Mitsue;McComb, J. Gordon
本研究获得了机构审查委员会的批准和知情同意。本研究符合HIPAA标准。本研究的目的是通过非增强磁共振成像技术无创地观察脑脊液（CSF）的运动。时间-空间标记反转脉冲（SLIP）技术应用于标记或标记感兴趣区域的CSF。在颅内和椎管间室进行脉冲标记后，在1500-4500 msec的反转时间内，标记的脑脊液清晰可见。在正常（n = 7）和改变（n = 2）生理条件下，使用非增强time-SLIP技术可以无创地观察脑脊液运动，包括体积和湍流。(c) RSNA， 2008年
Institutional review board approval and informed consent were obtained for this study. This study was HIPAA compliant. The purpose of this study was to visualize the movement of cerebrospinal fluid (CSF) noninvasively by using an unenhanced magnetic resonance imaging technique. A time-spatial labeling inversion pulse (SLIP) technique was applied to label, or tag, CSF in a region of interest. The tagged CSF was clearly visualized at inversion times of 1500-4500 msec after pulse labeling in both intracranial and intraspinal compartments. Noninvasive visualization of CSF movement, including bulk and turbulent flow, in normal (n = 7) and altered (n = 2) physiologic conditions was possible by using the unenhanced time-SLIP technique. (c) RSNA, 2008