Comparative susceptibilities of various animal-pathogenic mycoplasmas to fluoroquinolones
Comparative susceptibilities of various animal-pathogenic mycoplasmas to fluoroquinolones
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DOI：
10.1128/aac.41.9.2037
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发表时间：
1997-09-01
影响因子：
4.9
通讯作者：
Stegemann, M
中科院分区：
文献类型：
--
作者：
Hannan, PCT;Windsor, GD;Stegemann, M
研究了6种抗菌药物对不同地区禽、畜8种支原体162株的体外活性。Tiamulin的活性最高（MIC为90%，MIC(90)s, 0.025 ~ 0.25 μ g/ml）；恩诺沙星和丹氧氟沙星的活性相近（MIC(90)s, 0.05 ~ 1.0 μ g/ml），但比氟喹（MIC(90)s, 1 ~ 50 μ g/ml）的活性高得多。tylosin和土霉素的MIC(90)s分别为0.25 ~ 100 μ g/ml和0.25 ~ 100 μ g/ml。
The in vitro activities of six antimicrobial agents were tested against 162 mycoplasma strains of eight species isolated from poultry and livestock at different geographic sites. Tiamulin was most active (MICs at which 90% of the isolates were inhibited [MIC(90)s], 0.025 to 0.25 mu g/ml); enrofloxacin and danofloxacin had near equivalent activities (MIC(90)s, 0.05 to 1.0 mu g/ml), but were much more active than flumequine (MIC(90)s, 1 to 50 mu g/ml). The MIC(90)s of tylosin and oxytetracycline were 0.25 to > 100 mu g/ml and 0.25 to 100 mu g/ml, respectively.