Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat
Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat
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DOI：
10.1111/j.1440-1746.2005.03792.x
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发表时间：
2005-05
影响因子：
4.1
通讯作者：
Motoe Takayanagi;N. Sano;H. Takikawa
中科院分区：
文献类型：
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作者：
Motoe Takayanagi;N. Sano;H. Takikawa
背景与目的：奥美沙坦(RNH-6270)是一种新近开发的血管紧张素II受体拮抗剂，已有报道可通过粪便排泄。为了探讨奥美沙坦的胆汁排泄机制，我们研究了奥美沙坦在大鼠的胆汁排泄。
Background and Aim: Olmesartan (RNH‐6270) is a newly developed anigotensin II receptor antagonist, and has been reported to be excreted into feces. To examine the mechanism of the biliary excretion of olmesartan, we studied its biliary excretion in rats.