Invited Review: Genetics of Human Salivary Proteins

Invited Review: Genetics of Human Salivary Proteins
复制标题

特邀评论:人类唾液蛋白的遗传学

DOI:
--
复制
发表时间:
1989
期刊:
影响因子:
--
通讯作者:
A. Bennick
A. Bennick
中科院分区:
--
文献类型:
--
作者:
K. Minaguchi;A. Bennick

文献摘要

参考文献

被引文献

相似文献

在过去的15年中,我们在复杂混合物中区分单个蛋白质的能力有了快速的进步,分析蛋白质检测方法的灵敏度也大大提高。这导致了大量以前无法检测到的蛋白质的识别,并为蛋白质的研究开辟了新的可能性。随着这些现代分析技术的使用,唾液蛋白质组成的复杂性变得越来越明显,并促进了蛋白质多态性的研究和遗传模式的确定。与此同时,DNA重组技术的爆炸性进展使分析包括唾液中蛋白质在内的许多蛋白质的基因结构成为可能。虽然我们对唾液蛋白遗传学的理解还远未完成,但现有的知识使我们更好地了解基因中编码的信息导致分泌蛋白结构的方式。许多研究已经做了人类以及动物的唾液蛋白,但这篇评论将仅限于蛋白质的遗传学,据了解,是在人类唾液腺合成。
During the last 15 years, there has been a rapid advance in our ability to discriminate among individual proteins in complex mixtures, and the sensitivity of analytical protein detection methods has increased dramatically. This has led to the recognition of a large number of proteins that could not previously be detected and has opened up new possibilities for investigations of proteins. With such modern analytical techniques being used, the complexity of the composition of salivary proteins has become increasingly apparent and has facilitated studies on protein polymorphism and determination of patterns of inheritance. In parallel, the explosive advance in DNA recombinant technology has made it possible for the structure of the genes to be analyzed for a number of proteins, including those in saliva. While our understanding of the genetics of salivary proteins is far from complete, present knowledge gives us a much better insight into the manner in which the information encoded in the genes leads to the structure of the secreted proteins. Numerous studies have been done on human as well as animal salivary proteins, but this review will be limited to the genetics of proteins that, as far as is known, are synthesized in human salivary glands.
唾液中钙调节剂 statherin 基因的 cDNA 克隆和染色体定位 (4q11-13)。
DOI: --
发表时间: 1987
影响因子: 9.8
作者:
Sabatini,LM;Carlock,LR;Johnson,GW;Azen,EA
通讯作者: Azen,EA
多蛋白基因表达:神经内分泌肽多样性的产生。
DOI: 10.1146/annurev.bi.53.070184.003313
发表时间: 1984
影响因子: 16.6
作者:
Douglass,J;Civelli,O;Herbert,E
通讯作者: Herbert,E
人类唾液富含脯氨酸的蛋白质基因位于 12 号染色体上。
DOI: --
发表时间: 1985
影响因子: 9.8
作者:
Azen,EA;Goodman,PA;Lalley,PA
通讯作者: Lalley,PA
人类唾液富含脯氨酸的蛋白质基因系统中的差异RNA剪接和翻译后切割。
DOI: --
发表时间: 1985
期刊: The Journal of biological chemistry
影响因子: --
作者:
Maeda,N;Kim,HS;Azen,EA;Smithies,O
通讯作者: Smithies,O
富含酸性脯氨酸的人类唾液蛋白在钙磷灰石上的吸附热力学。
DOI: --
发表时间: 1982
期刊: The Journal of biological chemistry
影响因子: --
作者:
Moreno,EC;Kresak,M;Hay,DI
通讯作者: Hay,DI