Serial measurements of higher-order aberrations after blinking in normal subjects
Serial measurements of higher-order aberrations after blinking in normal subjects
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DOI：
10.1167/iovs.06-0018
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发表时间：
2006-08-01
影响因子：
4.4
通讯作者：
Tano, Yasuo
中科院分区：
文献类型：
--
作者：
Koh, Shizuka;Maeda, Naoyuki;Tano, Yasuo
目的。研究与眨眼相关的正常眼睛光学质量的连续变化。方法。使用波前传感器连续测量 20 名正常受试者的 20 只眼睛 30 秒的眼部高阶像差 (HOA)。测量期间，受试者被迫每 10 秒眨眼一次。所获得的像差数据在中心 4 毫米直径处进行类彗差、类球面和总 HOA 高达六阶泽尼克多项式的分析。结果。眨眼时 HOA 的连续变化按模式分为四组：稳定（25%）、小幅波动（45%）、锯齿状（20%）和其他（10%）。在具有锯齿图案的受试者中，总 HOA 随着眨眼之间的时间而显着增加（P < 0.001，单向重复测量方差分析）。具有锯齿图案的受试者中总 HOA 和彗形像差的增加表明，泪膜厚度的上下不对称变化是造成这种情况的原因。 结论。即使在临床正常的受试者中，眨眼后 HOA 的动态变化也表现出变化。 HOA 的连续测量可能有助于评估泪膜的动态变化以及眨眼后对视力质量的影响。
PURPOSE. To investigate sequential changes in the optical quality of normal eyes associated with blinking.METHODS. Ocular higher-order aberrations (HOAs) were measured sequentially by using a wavefront sensor for 30 seconds in 20 eyes of 20 normal subjects. During the measurement, subjects were forced to blink every 10 seconds. The obtained aberration data were analyzed in the central 4-mm diameter for coma-like, spherical-like, and total HOAs up to the sixth-order Zernike polynomials.RESULTS. The serial changes in the HOAs with blinking were classified into four groups by pattern: stable (25%), small-fluctuation (45%), sawtooth (20%), and others (10%). In the subjects with the sawtooth pattern, the total HOAs increased significantly (P < 0.001, one-way repeated-measures ANOVA) with time between blinks. Increased total HOAs and coma-like aberrations in the subjects with the sawtooth pattern suggested that the inferosuperior asymmetric change in tear film thickness is responsible.CONCLUSIONS. Dynamic changes in HOAs after blinking showed variations even in clinically normal subjects. Serial measurements of HOAs may be useful in evaluating the dynamic changes in tear film and the effects on the quality of vision after blinking.