INFLUENCE OF GENDER, BODY-MASS INDEX, AND AGE ON RESPONSE OF PLASMA-LIPIDS TO DIETARY-FAT PLUS CHOLESTEROL
INFLUENCE OF GENDER, BODY-MASS INDEX, AND AGE ON RESPONSE OF PLASMA-LIPIDS TO DIETARY-FAT PLUS CHOLESTEROL
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DOI：
10.1161/01.atv.12.8.955
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发表时间：
1992-08-01
期刊：
影响因子：
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通讯作者：
NESTEL, PJ
中科院分区：
文献类型：
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作者：
CLIFTON, PM;NESTEL, PJ
我们进行了一项交叉、随机、双盲饮食试验，检验性别影响血脂（特别是高密度脂蛋白（HDL）胆固醇）对膳食脂肪加胆固醇的反应的假设。26名男性和25名女性在年龄、低密度脂蛋白（LDL）胆固醇、甘油三酯和体重指数（BMI）方面相匹配。在2周的低脂肪（27%的卡路里），低胆固醇基线期后，受试者被给予两种等热量液体补充剂，每种3周，一种含有31 g脂肪（56%饱和）和650 mg胆固醇，另一种不含脂肪。女性的基线HDL 2胆固醇水平显著较高：0.41 mmol/l vs 0.26 mmol/l（p
We have conducted a crossover, randomized, double-blind dietary trial that tested the hypothesis that gender influences the response of plasma lipids, in particular high density lipoprotein (HDL) cholesterol, to dietary fat plus cholesterol. Twenty-six men and 25 women were matched for age, low density lipoprotein (LDL) cholesterol, triglyceride, and body mass index (BMI). After a 2-week baseline low-fat (27% of calories), low-cholesterol period, subjects were given two isocaloric liquid supplements for 3 weeks each, one containing 31 g fat (56% saturated) and 650 mg cholesterol, and the other fat free. The baseline HDL2 cholesterol level was significantly higher in women: 0.41 versus 0.26 mmol/l (p