CAVA SEPTI PELLUCIDI ET VERGAE - THEIR NORMAL AND PATHOLOGICAL STATES

CAVA SEPTI PELLUCIDI ET VERGAE - THEIR NORMAL AND PATHOLOGICAL STATES
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DOI:
10.1093/brain/92.1.213
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发表时间:
1969-01-01
期刊:
影响因子:
14.5
通讯作者:
ALVORD, EC
ALVORD, EC
中科院分区:
医学1区
文献类型:
--
作者:
SHAW, CM;ALVORD, EC

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透明隔内的空洞在尸检时很常见,通常认为在临床上无意义。透明隔腔和Vergee(1851)基本上是相同的结构,一个位于由穹窿柱形成的任意垂直平面的前方,另一个位于该垂直平面的后方。Thompson(1937)建议称一个腔为透明隔前腔,另一个腔为凸轮后腔,这将是一个更合乎逻辑的术语。这两个腔通常自由相通,但偶尔它们被彼此接近的穹窿柱分开。这种狭窄的交通被称为水管septi。空洞的大小差别很大,关于它们的发生率有相当大的分歧。直到最近才重新发现(Larroche和Baudey,1961),它们是正常的结构,经常出现在早产儿的正常大脑中,但在大多数个体中,在足月分娩前后收缩到一个消失的小裂缝,很容易被忽视。关于EQB的争议。这一结构的冷冻学,无论是在妊娠第三个月期间由迅速变宽的终板伸展形成的(Thompson,1937)或者仅仅是一个未能融合的半球间裂(Coming,1921年),已经解决了最近的研究Rakic和雅科夫列夫(1968年),他们已经表明,当胼胝体的纤维穿过中线时,在大脑半球的融合部位(端脑正中沟的堤岸)中,作为具有渐进性坏死的次级分裂,形成了脑腔。在一个非常特殊的情况下,隔膜可能只在一侧形成,“腔”仍然是软脑膜空间(Loeser和Alvord,1968),但通常腔不与软脑膜或心室空间相通。
CAVITES within the septum pellucidum are commonly seen at autopsy and are generally considered to'be clinically insigmficant. The cava septi pellucidi et Vergee (1851) are essentially the same structure, one being located anterior and the other posterior to an arbitrary vertical plane formed by the columns of the fornix. Thompson (1937) proposed calling one the cavum septi pellucidi anterius and the other the cam posterius, which would lx a more logical terminology. The two cavities usually communicate freely, but occasionally they are separated by the columns of the fornix which closely approximate each other. Such a narrow communication has been called the aqueduct septi. The cavities vary greatly in size, and there is considerable disagreement concerning their incidence. Only recently has it been rediscovered (Larroche and Baudey, 1961) that they are normal structures, constantly present in the premature normal brain but shrinking just before and after full term birth in most individuals to a vanishingly small slit which may easily be overlooked. The controversy concerning the eqb. ryology of this structure, whether formed by stretching of the rapidly widenjng lamina terminalis during the third month of gestation (Thompson, 1937) or being merely an interhemispheric fissure which fails to fuse (Coming, 1921), has been resolved by the recent studies of Rakic and Yakovlev (1968), who have shown that &e cavity develops in the site of fusion of the cerebral hemispheres (banks of the sulcus medianus telencephali medii) as a secondary cleavage with necrobiosis as the fibres of the corpus callosum cross the midline. In a very exceptional case, the septum may form on only one side, the" cavity" remaining as leptomeningial spaces (Loeser and Alvord, 1968), but normally the cavity does not communicate with either the leptomeningial or ventricular spaces.