Bioactivity of a CaO-SiO2 binary glasses system
Bioactivity of a CaO-SiO2 binary glasses system
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DOI：
10.1021/cm001107o
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发表时间：
2000-10-01
影响因子：
8.6
通讯作者：
Vallet-Regí, M
中科院分区：
文献类型：
--
作者：
Martínez, A;Izquierdo-Barba, I;Vallet-Regí, M
用溶胶-凝胶法制备了五种不同硅含量（50-90%）的CaO-SiO_2二元系统玻璃。采用热重-差热分析（TG/DTA）、傅里叶变换红外光谱（FTIR）、X射线衍射（XRD）、扫描电镜（SEM）、和能量色散谱（EDS）显示出低SiO2含量的这些玻璃之间在组成、比表面积和孔隙率方面的明显差异（熔体中50-70%）和具有高SiO2含量（熔体中80-90%）的那些。通过在37 ℃的模拟体液（SBF）中浸泡，对制备的所有玻璃进行体外生物活性研究。在体外分析之后，这些玻璃的表面的FTIR、XRD、SEM和EDS分析揭示了羟基碳酸盐磷灰石（HCA）层的形成。该层在玻璃上的形成过程是玻璃组成的函数。在具有较低SiO2（50- 70摩尔%）的那些玻璃中，形成速率增加。
Five glasses in the CaO-SiO2 binary system with different silica content (50-90% in mel) have been prepared by the sol-gel method. The referred glasses have been characterized by thermogravimetric and differential thermal analysis (TG/DTA), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction XRD), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS) showing clear differences in composition and specific surface and porosity between those glasses with low SiO2 content (50-70% in mel) and those with high SiO2 content (80-90% in mel). The in vitro bioactivity study of all glasses prepared were carried out by soaking in a simulated body fluid (SBF) at 37 degreesC. The FTIR, XRD, SEM, and EDS analysis of the surface of these glasses after the in vitro assays reveal the formation of a hydroxycarbonate apatite (HCA) layer. The formation process of this layer on the glass is a function of the glass composition. The rate of formation increases in those glasses with lower SiO2 (50-70% in mol).