Association between duration or etiology of gastroparesis and clinical response after gastric per-oral endoscopic pyloromyotomy
Association between duration or etiology of gastroparesis and clinical response after gastric per-oral endoscopic pyloromyotomy
复制标题
胃轻瘫持续时间或病因与经口内镜幽门肌切开术后临床反应的关系
DOI：
10.1016/j.gie.2018.12.023
复制
发表时间：
2019-05-01
影响因子：
7.7
通讯作者：
Cai, Qiang
中科院分区：
文献类型：
--
作者：
Mekaroonkamol, Parit;Patel, Vaishali;Cai, Qiang
Background and Aims: Gastric per-oral endoscopic pyloromyotomy(GPOEM) is a novel procedure with promising potential for the treatment of gastroparesis but with limited data regarding predictors of clinical response. This study aims to evaluate the safety and efficacy of the procedure and explore the impact of duration and etiology (diabetic vs nondiabetic) of gastroparesis on clinical outcome as measured by the Gastroparesis Cardinal Symptom Index (GCSI).Methods: A single-center retrospective longitudinal study at a tertiary care hospital was performed over an 18month period. Forty patients with refractory gastroparesis (25 nondiabetic and 15 diabetic patients) were included.Results: GCSI significantly improved throughout the study period (F[2.176, 17.405] = 10.152, P =.001). The nausea/vomiting subscale showed sustained improvement through 18 months (F[2.213, 17.704] = 15.863, P
