Characterization and bacterial response of zinc oxide particles prepared by a biomineralization process.
Characterization and bacterial response of zinc oxide particles prepared by a biomineralization process.
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DOI：
10.1021/jp808805w
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发表时间：
2009-04
期刊：
影响因子：
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通讯作者：
Danhong Yan;G. Yin;Zhongbing Huang;Mei Yang;Xiaoming Liao;Yunqing Kang;Yadong Yao;B. Hao;
中科院分区：
文献类型：
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作者：
Danhong Yan;G. Yin;Zhongbing Huang;Mei Yang;Xiaoming Liao;Yunqing Kang;Yadong Yao;B. Hao;
本文以丝素蛋白多肽为模板，通过简单的生物矿化过程，在室温下成功地合成了橄榄状的ZnO纳米粒子。SF肽在ZnO颗粒表面的包覆对其生物矿化过程中的形貌有着重要的影响。室温光致发光研究表明，随着矿化时间的延长，ZnO纳米粒子的可见蓝光发射峰在410 nm处增强。细菌学测试表明，矿化ZnO颗粒与SF肽是无毒的金黄色葡萄球菌，大肠杆菌和无乳链球菌，由于表面涂层的肽呈现良好的细胞相容性。其在生物光学探测器中的潜在应用前景可以预见。
In this paper, olive-like ZnO particles were successfully synthesized via a facile biomineralization process in the template of silk fibroin (SF) peptide at room temperature. The coat of SF peptide on the surface of ZnO particles had a substantial influence on their morphology during the biomineralization. Room-temperature photoluminescence behavior of ZnO particles indicated that the visible blue emission peak centered at 410 nm was enhanced with the mineralization time. Bacteriological tests revealed that the mineralized ZnO particles with SF peptide were not toxic for Staphylococcus aureus, Escherichia coli, and Streptococcus agalactiae, presenting good cytocompatibility due to the surface coat of peptide. Their potential applications in bio-optical detectors could be envisioned.