CHIRAL CROWN COMPLEXES CATALYZE MICHAEL ADDITION-REACTIONS TO GIVE ADDUCTS IN HIGH OPTICAL YIELDS
CHIRAL CROWN COMPLEXES CATALYZE MICHAEL ADDITION-REACTIONS TO GIVE ADDUCTS IN HIGH OPTICAL YIELDS
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DOI：
10.1039/c39810000625
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发表时间：
1981-01-01
影响因子：
--
通讯作者：
SOGAH, GDY
中科院分区：
文献类型：
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作者：
CRAM, DJ;SOGAH, GDY
与钾碱络合的手性冠醚以高转换数催化β-酮酯与甲基乙烯基酮和两种苯乙酸酯与丙烯酸甲酯的迈克尔加成，得到光学纯度为99-60%的产物，其构型偏差基于空间效应可合理化。
Chiral crowns complexed to potassium bases catalyse with high turnover numbers the Michael additions of a β-ketoester to methyl vinyl ketone, and of two phenylacetic esters to methyl acrylate, to give products of 99–60% optical purity with a configurational bias rationalizable on the basis of steric effects.