The HP1 protein family: getting a grip on chromatin
The HP1 protein family: getting a grip on chromatin
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HP1 蛋白家族：掌控染色质
DOI：
10.1016/s0959-437x(00)00058-7
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发表时间：
2000-04-01
影响因子：
4
通讯作者：
Elgin, SCR
中科院分区：
文献类型：
--
作者：
Eissenberg, JC;Elgin, SCR
HP1是一种异染色质相关蛋白，在异染色质诱导的基因沉默中具有剂量依赖性作用。HP1和其他蛋白质之间的一些有趣的相互作用已经被描述，暗示HP1在基因调控，DNA复制和核结构。
HP1 was first described in Drosophila as a heterochromatin-associated protein with dosage-dependent effects on heterochromatin-induced gene silencing, Recently, membership of the HP1 protein family has expanded tremendously. A number of intriguing interactions between HP1 and other proteins have been described, implicating HP1 in gene regulation, DNA replication, and nuclear architecture.