Race, pain, and opioids among patients with chronic pain in a safety-net health system.

Race, pain, and opioids among patients with chronic pain in a safety-net health system.
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DOI:
10.1016/j.drugalcdep.2021.108671
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发表时间:
2021-05-01
影响因子:
4.2
通讯作者:
Coffin PO
Coffin PO
中科院分区:
医学2区
文献类型:
--
作者:
Haq N;McMahan VM;Torres A;Santos GM;Knight K;Kushel M;Coffin PO

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最近美国阿片类药物处方做法的变化可能会加剧黑人与白人患者在阿片类药物获取方面的差异。为了评估阿片类药物处方和管理方面的种族差异,我们使用了 2017 年至 2019 年收集的基线数据,对患有慢性非癌症疼痛和有非法药物使用史的患者进行纵向队列分析。对黑人和白人参与者的社会人口学特征、疼痛、心理困扰、药物使用和阿片类药物处方实践进行了比较。我们以种族为结果进行了多变量逻辑回归。我们还按种族比较了黄旗事件(与阿片类药物相关的急诊科就诊、尿液药物筛查中的非法物质、相关行为的提供者记录)。超过一半的分析参与者是黑人(57%),其余的是白人(43%)。过去三个月平均疼痛较严重的参与者(调整后优势比 [AOR]:1.29,95%CI:1.08-1.55,p=0.006)成为黑人的几率较高。去年注射吸毒(AOR:0.39,95%CI:0.16-0.94,p = 0.04)和过去一年阿片类药物最大剂量(每 10 吗啡毫克当量(MME)的 AOR:0.99,95%CI:0.98-1.00,p = 0.006)较高与黑人的几率较低相关。我们发现在使用阿片类药物管理措施或基于黄旗事件停止使用阿片类药物方面没有种族差异。尽管平均疼痛较高且注射药物使用较少,但去年最大 MME 剂量较低,可能代表黑人患者对开阿片类药物治疗慢性疼痛存在偏见。这可能是由于未测量的隐性提供者偏见或患者层面的因素(例如,利用非阿片类药物疼痛应对策略或不太可能要求额外的阿片类药物)。
Recent changes in opioid prescribing practices in the US may exacerbate disparities in opioid access among Black compared to White patients. To evaluate racial disparities in opioid prescribing and stewardship, we used baseline data collected from 2017 to 2019 for a longitudinal cohort of patients with chronic non-cancer pain and a history of illicit substance use. Sociodemographic characteristics, pain, psychological distress, substance use, and opioid prescription practices were compared between Black and White participants. We conducted multivariable logistic regression with race as the outcome. We also compared yellow flag events (opioid-related emergency department visits, illicit substances on urine drug screens, provider-documentation of concerning behaviors) by race. Over half of participants analyzed were Black (57%) and the remainder White (43%). Participants with worse average pain in the past three months (adjusted odds ratio [AOR]:1.29, 95%CI:1.08-1.55, p=0.006) had higher odds of being Black. Past-year injection drug use (AOR:0.39, 95%CI:0.16-0.94, p=0.04) and a higher past-year maximum opioid dose (AOR per 10 morphine milligram equivalents (MME):0.99, 95%CI:0.98-1.00, p=0.006) were associated with lower odds of being Black. We found no differences by race in the use of opioid stewardship measures or discontinuation of opioids based on yellow flag events. Lower past-year maximum MME dose, despite higher average pain and less injection drug use, may represent bias away from prescribing opioids for chronic pain among Black patients. This could be due to unmeasured implicit provider bias or patient-level factors (e.g., utilizing non-opioid pain coping strategies or being less likely to request additional opioids).
DOI: 10.1093/pm/pny137
发表时间: 2019-08-01
期刊: PAIN MEDICINE
影响因子: 3.1
作者:
Buonora, Michele;Perez, Hector R.;Starrels, Joanna L.
通讯作者: Starrels, Joanna L.
DOI: 10.1371/journal.pone.0232538
发表时间: 2020-05-04
期刊: PLOS ONE
影响因子: 3.7
作者:
Coffin, Phillip O.;Rowe, Christopher;Vittinghoff, Eric
通讯作者: Vittinghoff, Eric
DOI: 10.1111/acem.13214
发表时间: 2017-08-01
影响因子: 4.4
作者:
Dehon, Erin;Weiss, Nicole;Sterling, Sarah
通讯作者: Sterling, Sarah
DOI: 10.1016/j.jval.2019.09.2748
发表时间: 2020-02-01
期刊: VALUE IN HEALTH
影响因子: 4.5
作者:
Price-Haywood, Eboni G.;Burton, Jeffrey;Bazzano, Lydia
通讯作者: Bazzano, Lydia
CDC规定慢性疼痛的阿片类药物的指南 - 美国,2016年。
DOI: 10.1001/jama.2016.1464
发表时间: 2016-04-19
期刊: JAMA
影响因子: --
作者:
Dowell D;Haegerich TM;Chou R
通讯作者: Chou R