Shared and disease-specific glial gene expression changes in neurodegenerative diseases.

Shared and disease-specific glial gene expression changes in neurodegenerative diseases.
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神经退行性疾病中共享的和疾病特异性的神经胶质基因表达变化。

DOI:
10.1038/s43587-023-00378-1
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发表时间:
2023
期刊:
Nature aging
影响因子:
--
通讯作者:
Zhao,Guoyan
Zhao,Guoyan
中科院分区:
--
文献类型:
--
作者:
Zhao,Guoyan

文献摘要

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We found evolutionarily conserved astrocyte and microglia subpopulations shared across multiple brain regions. We reveal similarities and differences between Alzheimer’s disease glia and Parkinson’s disease glia, as well as regional variance linked to disease pathology and neurodegeneration.