Homology modeling of glycosyl hydrolase family 18 enzymes and proteins
Homology modeling of glycosyl hydrolase family 18 enzymes and proteins
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DOI：
10.1021/ci970236v
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发表时间：
1997-11-01
期刊：
影响因子：
--
通讯作者：
Madura, JD
中科院分区：
文献类型：
--
作者：
Aronson, NN;Blanchard, CJ;Madura, JD
利用最先进的同源模建方法，确定了三个18糖基水解酶家族的三维坐标。利用来自SmChiA的X射线坐标，计算机确定了Gp39、Brp39和壳三糖苷酶的结构。评估了建模工作的结果，并将建模的结构与其他已知族18成员进行了比较。
Using state-of-the-art homology modeling methods, three-dimensional coordinates for three family 18 glycosyl hydrolases were determined. The structures for Gp39, Brp39, and chitotriosidase were computer determined using the X-ray coordinates from SmChiA. The results of the modeling efforts are assessed, and comparison of the modeled structures to other known family 18 members is made.