Modulation of liver graft hemodynamics by partial ablation of the splenic circuit: a way to increase hepatic artery flow?

Modulation of liver graft hemodynamics by partial ablation of the splenic circuit: a way to increase hepatic artery flow?
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通过部分消融脾回路来调节肝移植血流动力学:增加肝动脉流量的方法?

DOI:
10.1016/s0041-1345(00)02547-1
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发表时间:
2001
影响因子:
0.9
通讯作者:
B. de Hemptinne
B. de Hemptinne
中科院分区:
医学4区
文献类型:
--
作者:
R. Troisi;E. Hoste;P. Van Langenhove;J. Decruyenaere;D. Voet;U. Hesse;O. Cuomo;B. de Hemptinne

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结果 再灌注前后 CO 和平均动脉压没有差异(表 1),显示移植过程中血流动力学完全稳定。然而,结扎脾动脉后,肝脏血流动力学在总肝血流、HAF 和门静脉血流方面发生了重要变化(表 2)。 HAF 从 80·52 增加到 151·84 mL/min (P. 02)。 PVF从2.64±1.28下降到1.65±0.78L/min(P.06)。多普勒超声评估显示术后平均 HAF 速度为 102·66 厘米/秒,而测量的平均 PVF 为 1301·491 毫升/分钟。仅一名患者出现无症状血清淀粉酶升高(生化性胰腺炎)
RESULTSNo differences in CO and mean arterial pressure before and after reperfusion were noticed (Table 1), showing a complete hemodynamic stability during the transplant procedure. However, the ligature of the splenic artery was followed by important variations in hepatic hemodynamics in terms of total liver blood ffow, HAF, and portal vein ffow (Table 2). HAF increased from 80 52 to 151 84 mL/min (P. 02). PVF decreased from 2.64 1.28 to 1.65 0.78 L/min (P. 06). Doppler US evaluation showed postoperatively a mean HAF velocity of 102 66 cm/sec, whereas the mean PVF measured was of 1301 491 mL/min. Asymptomatic increase of serum amylase (biochemical pancreatitis) was recorded in only one patient