EXPERIMENTAL-INFECTION OF CASTRATED LAMBS WITH MYCOPLASMA-AGALACTIAE
EXPERIMENTAL-INFECTION OF CASTRATED LAMBS WITH MYCOPLASMA-AGALACTIAE
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DOI：
10.1017/s0022172400065050
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发表时间：
1984-01-01
影响因子：
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通讯作者：
HUNTER, AR
中科院分区：
文献类型：
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作者：
MACOWAN, KJ;BRAND, TF;HUNTER, AR
6月龄组的实验感染过程用M.对法国产无乳链球菌进行7个月的培养和血清学随访。通过不同途径接种和接触暴露后，绵羊田间分离株的感染与山羊田间分离株引起的感染进行了比较。除了在一只接种绵羊分离株的动物中出现有限的关节炎和在另一只接种山羊分离株的动物中出现流泪增加外，所产生的长期感染是无症状的。绵羊分离株的毒力更强，因为生物体的宰前和宰后回收率更一致，血清学反应更明显。血清学反应在动物之间和菌株感染之间存在差异，薄膜抑制试验的结果比补体结合试验的结果更一致。这两个测试检测载体感染的局限性进行了讨论。
The course of experimental infection in groups of 6-mo.-old castrated lambs with field isolates of M. agalactiae from France was followed culturally and serologically for 7 mo. Infection with an ovine field isolate following inoculation by different routes and contact exposure was compared with that caused similarly by a caprine field isolate. The prolonged infections produced were symptomless apart from limited arthritis in one animal inoculated with the isolate from sheep and increased lachrymation in another associated with the goat isolate. The ovine isolate was more virulent in that ante- and postmortem recoveries of the organism were more consistent and the serological responses more pronounced. Serological responses varied between animals and between strain infections, and the results of the film inhibition test were more consistent than those of the complement fixation test. The limitations of both these tests for detecting carrier infections are discussed.