Birthweight in Offspring of Mothers with High Prevalence of Helminth and Malaria Infection in Coastal Kenya

Birthweight in Offspring of Mothers with High Prevalence of Helminth and Malaria Infection in Coastal Kenya
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DOI:
10.4269/ajtmh.2012.12-0371
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发表时间:
2013-01-01
影响因子:
3.3
通讯作者:
Malhotra, Indu
Malhotra, Indu
中科院分区:
医学4区
文献类型:
--
作者:
Fairley, Jessica K.;Bisanzio, Donal;Malhotra, Indu

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关于母体蠕虫感染和疟疾-蠕虫合并感染对分娩结果的关系的研究结果好坏参半。从肯尼亚夸莱地区招募了696名孕妇,并在分娩时对她们进行了疟疾和寄生虫感染检测。记录了664名婴儿的出生体重。恶性疟原虫感染率为42.7%,血血吸虫感染率为30.6%,丝虫病感染率为36.2%,钩虫感染率为31.5%,毛线虫感染率为5.9%;合并感染占46.7%。15.4%的后代存在低出生体重(LBW)(体重< 2500克),8.3%的后代有体重z分数
Results of studies on the associations of maternal helminth infection and malaria-helminth co-infection on birth outcomes have been mixed. A group of 696 pregnant women from the Kwale district in Kenya were recruited and tested for malaria and helminth infection at delivery. Birthweight was documented for 664 infants. A total of 42.7% of the mothers were infected with Plasmodium falciparum, 30.6% with Schistosoma haematobium, 36.2% with filariasis, 31.5% with hookworm, and 5.9% with Trichuris trichiura; co-infection was present in 46.7%. Low birthweight (LBW) (weight < 2,500 grams) was present in 15.4% of the offspring, and 8.3% had a weight z-score