Simultaneous infections with human T cell leukemia virus type I and the human immunodeficiency virus.
Simultaneous infections with human T cell leukemia virus type I and the human immunodeficiency virus.
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同时感染人类T细胞白血病病毒I型和人类免疫缺陷病毒。
DOI：
10.1093/infdis/155.4.617
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Parks,WP
中科院分区：
文献类型：
--
作者：
Kanner,SB;Parks,ES;Scott,GB;Parks,WP
来自四个不同家庭的四名成年人被发现同时感染了人类T细胞白血病病毒I型(HTLV-I)和人类免疫缺陷病毒(HIV)。这些人对HTLV-Ienv跨膜蛋白p21E血清阳性，并且都有对HTLV-I核心多肽p24的抗体。所有四名患者都有针对HIV跨膜多肽p41E和HIV核心多肽p24的抗体。HTLV-I是从所有四个人的外周血淋巴细胞中分离出来的，两种病毒都是从其中两个人身上分离出来的。在家庭接触者中发现了艾滋病毒传播的证据。这四名成年人中的10名儿童中有8名艾滋病毒血清阳性，可能是因为受感染母亲的围产期传播。这些成年人的五名配偶中有两名接受了检查；这些配偶对艾滋病毒有抗体，病毒呈阳性。在这些家庭中没有发现HTLV-I传播的证据。
Four adults from four separate households were found to have simultaneous retroviral infections with human T cell leukemia virus type I (HTLV-I) and human immunodeficiency virus (HIV). These individuals were seropositive for the HTLV-Ienvtransmembrane protein p21E, and all had antibodies to the HTLV-I core polypeptide p24. All four patients also had antibodies to the HIVenvtransmembrane polypeptide p41E and to the HIV core polypeptide p24. HTLV-I was isolated from peripheral blood lymphocytes of all four individuals, and both viruses were isolated from two of them. Evidence of HIV transmission was noted in the family contacts. Eight of 10 children of these four adults were seropositive for HIV, presumably because of perinatal transmission from infected mothers. Two of five spouses of these adults were examined; these spouses had antibodies to HIV and were positive for virus. No evidence of HTLV-I transmission was noted in these families.