Changes in human knee ligament stiffness secondary to osteoarthritis
Changes in human knee ligament stiffness secondary to osteoarthritis
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DOI：
10.1016/s0736-0266(01)00087-0
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发表时间：
2002-03-01
影响因子：
2.8
通讯作者：
Ziv, I
中科院分区：
文献类型：
--
作者：
Fishkin, Z;Miller, D;Ziv, I
比较了一组10例因内翻退行性骨关节炎（OAP）接受全膝关节置换术的患者、一组10例骨关节炎尸体膝关节（OAC）和一组10例非骨关节炎尸体膝关节（NOA）的内侧（MCL）和外侧（LCL）侧副韧带刚度。使用器械化莫兰撑开器获得每个膝关节内侧和外侧间室的载荷-伸长曲线。将应变计（SG）连接到撑开器手柄上，并将应变校准为施加在撑开距离上的载荷。在延伸。OAR、OAC和NOA组的内侧室刚度分别为60.7 +/- 16、52.8 +/- 93和21.4 +/- 5.0 N/mm。对于OAP，伸展时的外侧间室刚度为29.2 +/- 9.2、33.3 +/- 10.3和19.5 +/- 5.3 N/mm。OAC。NOA的。分别OAP和OAC组之间的刚度差异无统计学意义（p > 0.05）。然而，与NOA组相比，骨关节炎组（OAP和OAC）的韧带硬度在统计学上显著增加（p < 0.05）。膝关节置换术后，伸展时内侧结构较硬可能导致屈曲挛缩和加速聚乙烯磨损。充分的骨切除，结合软组织松解，可以缓解继发于OA的内侧间室中观察到的刚度增加三倍，而不会危及关节稳定性。(C)2002骨科研究学会。由爱思唯尔科技有限公司出版。保留所有权利。
Stiffness of the medial (MCL) and lateral (LCL) collateral ligaments was compared between a group of 10 patients undergoing total knee arthroplasty for varus degenerative osteoarthritis (OAP), a group of 10 osteoarthritic cadaveric knees (OAC), and a group of 10 non-osteoarthritic cadaveric knees (NOA). A load-elongation curve was obtained for the medial and lateral compartments of each knee using an instrumented Moreland spreader. A strain gage (SG) was attached to the spreader handle and strain was calibrated to load applied against the spread distance. In extension. medial compartment stiffness of the OAR OAC, and NOA groups was 60.7 +/- 16, 52.8 +/- 93 and 21.4 +/- 5.0 N/mm. respectively. Lateral compartment stiffness in extension was 29.2 +/- 9.2 33.3 +/- 10.3 and 19.5 +/- 5.3 N/mm, for OAP. OAC. and NOA. respectively. Differences in stiffness between the OAP and OAC groups were not statistically significant (p > 0.05). However, the osteoarthritic groups (OAP and OAC) demonstrated a statistically significantly (p < 0.05) increase in ligament stiffness when compared to the NOA group. Following knee arthroplasty, stiffer medial structures in extension may lead to flexion contracture and accelerated polyethylene wear. Adequate bone resection, in conjunction with soft tissue release may alleviate the threefold increase in stiffness observed in the medial compartment secondary to OA without jeopardizing joint stability. (C) 2002 Orthopaedic Research Society. Published by Elsevier Science Ltd. All rights reserved.