Guiding Cell Attachment in 3D Microscaffolds Selectively Functionalized with Two Distinct Adhesion Proteins

Guiding Cell Attachment in 3D Microscaffolds Selectively Functionalized with Two Distinct Adhesion Proteins
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DOI:
10.1002/adma.201604342
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发表时间:
2017-02-02
期刊:
影响因子:
29.4
通讯作者:
Bastmeyer, Martin
Bastmeyer, Martin
中科院分区:
材料科学1区
文献类型:
--
作者:
Richter, Benjamin;Hahn, Vincent;Bastmeyer, Martin

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将三种不同的光致抗蚀剂组合到单个直接激光写入的3D微支架中,可以用两种生物活性全长蛋白质进行功能化。细胞指导性微支架由配备有具有不同蛋白质结合特性的光活化成分的钝化框架组成。这允许3D中上皮细胞或成纤维细胞的定向细胞附着。
The combination of three different photoresists into a single direct laser written 3D microscaffold permits functionalization with two bioactive fulllength proteins. The cell-instructive microscaffolds consist of a passivating framework equipped with light activatable constituents featuring distinct proteinbinding properties. This allows directed cell attachment of epithelial or fibroblast cells in 3D.