Ethylenethiourea in urine as an indicator of exposure to mancozeb in vineyard workers
Ethylenethiourea in urine as an indicator of exposure to mancozeb in vineyard workers
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DOI：
10.1016/s0378-4274(02)00182-0
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发表时间：
2002-08-05
影响因子：
3.5
通讯作者：
Maroni, M
中科院分区：
文献类型：
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作者：
Colosio, C;Fustinoni, S;Maroni, M
在本研究中，个人接触代森锰锌和/或乙烯利（ETU）在13个意大利葡萄园工人和13个主题没有职业接触农药进行了调查。为此，测定了尿中ETU的水平和皮肤接触代森锰锌的情况。基线尿ETU结果低于所有对照组（< 0.5 mug/g肌酐）和10名工人（中位数< 0.5，范围< 0.5-3.4 mug/g肌酐）的分析检测限。在工人中，与基线水平相比，轮班结束时尿ETU显著增加（2.5，< 0.5-95.2 mug/g肌酐）。使用开放式牵引器的操作者（n = 7）的位移末期尿ETU高于使用封闭式牵引器的操作者（n = 5）（16.2 vs. 2.4 mug/g肌酐），但差异不显著（P = 0.073）。尿ETU与衣服和皮肤上测定的代森锰锌皮肤暴露呈正相关（分别为斯皮尔曼p = 0.770和0.702，P = 0.009和0.024）。葡萄酒的消费正影响ETU的排泄。(C)2002爱思唯尔科学爱尔兰有限公司保留所有权利。
In the present study, the personal exposure to mancozeb and/or ethilenethiourea (ETU) in 13 Italian vineyard workers and in 13 subjects without occupational exposure to pesticides was investigated. With this aim, the level of ETU in urine and the dermal exposure to mancozeb were determined. Baseline urinary ETU results were lower than the analytical limit of detection for all controls ( < 0.5 mug/g creatinine) and for ten workers (median < 0.5, range < 0.5-3.4 mug/g creatinine). In workers, urinary ETU was significantly increased at the end of shift (2.5, < 0.5-95.2 mug/g creatinine) compared with baseline levels. End-shift urinary ETU was higher in operators using open tractors (n = 7) than in those using closed tractors (n = 5) (16.2 vs. 2.4 mug/g creatinine), but the difference was not significant (P = 0.073). End-shift urinary ETU was positively correlated with dermal exposure to mancozeb determined both over the clothes and on the skin (Spearman's p = 0.770 and 0.702, P = 0.009 and 0.024, respectively). Wine consumption positively influenced the excretion of ETU. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.