De visione, voce et auditu: the contribution of Hieronymous Fabricius to our understanding of tensor tympani function.
De visione, voce et auditu: the contribution of Hieronymous Fabricius to our understanding of tensor tympani function.
复制标题
Devisione,voceetaudtu：HieronymousFabricius 对我们理解鼓室张量功能的贡献。
DOI：
10.1097/mao.0b013e3181bc35b3
复制
发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Lee,DanielJ
中科院分区：
文献类型：
--
作者：
Mukerji,Sudeep;Lee,DanielJ
研究设计：本研究回顾了有关法布里修斯（1533-1619）生平和科学贡献的文献。我们还分析了法布里修斯第一版题为《视觉、声音和听觉》（the Vision, Voice and Hearing, 1600）的书中关于中耳肌肉的拉丁文翻译文本。结果：法布里修斯是最早将结构-功能关系引入解剖学研究的科学家之一。他对静脉瓣膜和人类胎儿发育的描述更为人所知，他对耳科的主要贡献是他关于鼓室张量（TT）功能的理论。自维萨里乌斯（1514-1564）发现和尤斯塔奇斯（1510-1574）描述后，人们对其功能进行了长时间的猜测。法布里修斯的TT生理学理论在他的专著《视觉、声音和听觉》（1600）中有描述。他写道，TT“保护”了鼓膜，有助于中耳通气。20世纪，Otto Metz（1905-1993）发明了声阻抗测量桥，首次实现了对中耳功能的客观测量。对各种耳部病变的人进行的实验证实，镫骨肌是中耳诱发声的主导肌。然而，基于最近的生理学、胚胎学和组织学研究，fabicius关于TT在中耳通气中的作用的原始理论一直持续到今天。结论：耶罗姆斯·法布里修斯是从结构-功能关系角度探讨解剖学的先驱，是为学生提供最大限度学习环境的积极倡导者。法布里修斯的著作为当代关于耳部作用的理论奠定了基础，他提出这些观点时，我们对耳部解剖学和生理学的理解正取得巨大进步。
Study Design:This work reviews the literature concerning the life and scientific contributions of Hieronymous Fabricius (1533-1619). We also analyze the translated Latin text that focuses on the middle ear muscles from a first edition of Fabricius' book entitled De Visione, Voce et Auditu (The Vision, Voice and Hearing, 1600).Results:Hieronymous Fabricius was one of the first scientists to introduce structure-function relationships in anatomic research. Better known for his descriptions of venous valves and human fetal development, his major contribution to otology was his theory on tensor tympani (TT) function. The TT is 1 of 2 middle ear muscles whose function has undergone a long period of speculation since its discovery by Vesalius (1514-1564) and description by Eustachius (1510-1574). Fabricius' theory of TT physiology was described in his treatise De Visione, Voce et Auditu (1600). He wrote that the TT" protected" the tympanic membrane and helped in middle ear ventilation. In the 20th century, the development of the acoustic impedance measuring bridge by Otto Metz (1905-1993) allowed for the first objective measurements of middle ear function. Experiments on human subjects with various ear pathologies confirmed that the stapedius was the dominant sound evoked middle ear muscle. However, Fabricius' original theory on the TT's role in middle ear ventilation persists to this day based on recent physiologic, embryologic, and histologic studies.Conclusion:Hieronymous Fabricius was a pioneer in approaching anatomy from a structure-function relationship, and was an active proponent for maximizing the learning environment for students. Fabricius' writings provided the foundation for contemporary theories on the role of the TT, and he proposed those ideas during an era when great strides were being made to increase our understanding of ear anatomy and physiology.