Normal values and standardization of parameters in nuclear cardiology: Japanese Society of Nuclear Medicine working group database.
Normal values and standardization of parameters in nuclear cardiology: Japanese Society of Nuclear Medicine working group database.
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DOI：
10.1007/s12149-016-1065-z
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发表时间：
2016-04
影响因子：
2.6
通讯作者：
Okuda K
中科院分区：
文献类型：
--
作者：
Nakajima K;Matsumoto N;Kasai T;Matsuo S;Kiso K;Okuda K
作为日本核医学会工作组活动的一个为期两年的项目，积累和总结了正常心肌影像数据库。门控和非门控负荷静息图像集用于心肌灌注成像，可用于心肌灌注缺损度评分和正常左心功能分析。对于采用多焦点准直器设计的单光子发射计算机断层扫描(SPECT)，建立了仰卧位和俯卧位的数据库以及基于CT的衰减校正。基于CT的校正提供了不同性别之间相似的血流灌注模式。在门控心肌灌注SPECT的相位分析中，用四个软件程序确定了相位带宽、标准差和熵的正常范围，这是一种分析不同步的新方法。尽管结果不可互换，但性别、射血分数和容量是这些参数的共同特征。使用校准模体法对123I-MIBG交感神经显像的心脏-纵隔比(HMR)进行标准化。任何类型的准直器的HMR都可以换算成具有中等能量可比准直器的值。以常用的正常数据库和标准技术为基础进行适当的量化，可以在临床实践和研究中发挥关键作用。
As a 2-year project of the Japanese Society of Nuclear Medicine working group activity, normal myocardial imaging databases were accumulated and summarized. Stress-rest with gated and non-gated image sets were accumulated for myocardial perfusion imaging and could be used for perfusion defect scoring and normal left ventricular (LV) function analysis. For single-photon emission computed tomography (SPECT) with multi-focal collimator design, databases of supine and prone positions and computed tomography (CT)-based attenuation correction were created. The CT-based correction provided similar perfusion patterns between genders. In phase analysis of gated myocardial perfusion SPECT, a new approach for analyzing dyssynchrony, normal ranges of parameters for phase bandwidth, standard deviation and entropy were determined in four software programs. Although the results were not interchangeable, dependency on gender, ejection fraction and volumes were common characteristics of these parameters. Standardization of 123I-MIBG sympathetic imaging was performed regarding heart-to-mediastinum ratio (HMR) using a calibration phantom method. The HMRs from any collimator types could be converted to the value with medium-energy comparable collimators. Appropriate quantification based on common normal databases and standard technology could play a pivotal role for clinical practice and researches.