COMBINED VITAMIN-A AND VITAMIN-E THERAPY PREVENTS RETINAL ELECTRO-PHYSIOLOGICAL DETERIORATION IN A-BETA-LIPOPROTEINAEMIA
COMBINED VITAMIN-A AND VITAMIN-E THERAPY PREVENTS RETINAL ELECTRO-PHYSIOLOGICAL DETERIORATION IN A-BETA-LIPOPROTEINAEMIA
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DOI:
10.1136/bjo.66.12.767
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发表时间:
1982-01-01
影响因子:
4.1
通讯作者:
DECKELBAUM, RJ
中科院分区:
文献类型:
--
作者:
BISHARA, S;MERIN, S;DECKELBAUM, RJ
Eight patients with abetalipoproteinemia had the typical ocular, systemic and laboratory findings of this disease. Combined therapy with vitamins A and E was administered, starting as early as the 1st day of life and as late as 26 yr of age. The patients were followed up for 2-6 yr. Electroretinography was undertaken in all cases and electrooculography in some. After initiation of vitamin A and E therapy no progression of disturbed visual function could be detected in any patient. These objective tests of retinal function demonstrated that the combined vitamin A and E therapy may be useful in arresting retinal deterioration in abetalipoproteinemia.