Pathogenesis of the verruga of Carrion's disease. Ultrastructural studies.
Pathogenesis of the verruga of Carrion's disease. Ultrastructural studies.
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腐肉病疣的发病机制。
DOI：
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发表时间：
1972
影响因子：
6
通讯作者：
H. Lumbreras
中科院分区：
文献类型：
--
作者：
S. Recavarren;H. Lumbreras
五名患有“爆发型”腐肉病的患者被发现在疣状体的细纤维间质中有细菌。观察到疣状细胞吞噬生物体的特征。这种细菌很可能是巴尔通体，因为它们与在疾病的血液阶段寄生于红细胞的巴尔通体相似。很可能在血肿期之后，未知的机制（可能与免疫有关）驱使巴尔通体生物体进入皮肤，在疣状组织中被破坏和消除。这表明，疣状组织的发展是为了消除巴尔通体在疾病的组织阶段。
Five patients having the "eruptive form" of Carrion's disease were found to have bacteria in the fine fibrillar interstitium of the verrugas. Features suggesting phagocytosis of the organisms by the verruga cells were observed. The bacteria are probably Bartonella because they are similar to Bartonella that parasitize red blood cells in the hematic phase of the disease. It is likely that after the hematic phase, unknown mechanisms, probably related to immunity, drive Bartonella organisms to the skin where they are destroyed and eliminated in the verrucous tissue. This suggests that verrucous tissue develops in order to eliminate Bartonella during the tissue phase of the disease.