DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation.
DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation.
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DOI:
10.1111/tid.12177
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发表时间:
2014-02
期刊:
影响因子:
--
通讯作者:
Tan CS
中科院分区:
文献类型:
--
作者:
Chalkias S;Mackenzie MR;Gay C;Dooley C;Marty FM;Moss RB;Li T;Routh RL;Walsh SR;Tan CS
Parainfluenza infection is a cause of significant morbidity and mortality in allogeneic hematopoietic stem cell transplant (HSCT) patients. DAS181 is a novel antiviral agent with activity against influenza and parainfluenza. We report the first 2 cases, to our knowledge, of successful DAS181 use in ventilated HSCT patients with severe parainfluenza lung disease.
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