Eradication of resident bacteria of normal human skin by antimicrobial ointment
Eradication of resident bacteria of normal human skin by antimicrobial ointment
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DOI：
10.1128/aac.47.6.1988-1990.2003
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发表时间：
2003-06-01
影响因子：
4.9
通讯作者：
Ashe, KM
中科院分区：
文献类型：
--
作者：
Hendley, JO;Ashe, KM
局部使用三联抗生素软膏（含有新霉素、多粘菌素和杆菌肽）可根除角质层 25 层的常驻细菌，并可在一夜之间（但 1 周后）阻止细菌重新繁殖。通过 15 层，莫匹罗星有一定效果，而双抗生素软膏则没有效果。皮脂腺中的常驻细菌库不受局部抗生素的影响。
The application of a topical triple-antibiotic ointment (containing neomycin, polymyxin, and bacitracin) eradicated resident bacteria through 25 layers of the stratum corneum and prevented repopulation of bacteria overnight but not at 1 week. Through 15 layers, mupirocin had some effect, whereas a double-antibiotic ointment had none. The reservoir of resident bacteria in the sebaceous glands is not affected by a topical antibiotic.