High willingness to use rapid fentanyl test strips among young adults who use drugs.
High willingness to use rapid fentanyl test strips among young adults who use drugs.
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DOI：
10.1186/s12954-018-0213-2
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发表时间：
2018-02-08
影响因子：
4.4
通讯作者：
Marshall BDL
中科院分区：
文献类型：
--
作者：
Krieger MS;Yedinak JL;Buxton JA;Lysyshyn M;Bernstein E;Rich JD;Green TC;Hadland SE;Marshall BDL
自2013年以来，美国年轻人中合成阿片类药物过量死亡率上升了300%以上，主要原因是海洛因和其他药物被非法制造的芬太尼污染。快速试纸可用于检测药物样本（使用前）或尿液（使用后）中芬太尼的存在，这可能有助于告知人们他们的暴露风险。本研究的目的是确定使用药物的年轻人是否愿意使用快速试纸作为减少危害的干预措施，以防止过量使用。我们假设那些服用过量的人会更愿意使用试纸。我们在2017年5月至9月期间招募了罗德岛吸毒的年轻人作为方便样本。符合条件的参与者（年龄在18至35岁之间，过去30天使用过药物）完成了访谈者管理的调查。该调查评估了参与者的社会人口统计学和行为特征，过量风险，以及疑似芬太尼暴露，以及使用带回家的快速试纸检测药物或尿液中芬太尼污染的意愿。然后，参与者接受了使用试纸的培训，并被要求带回家10张。在93名符合条件的参与者中，平均年龄为27岁（SD = 4.8）， 56% （n = 52）的参与者为男性，56% （n = 52）的参与者为白人。超过三分之一（n = 34,37%）有过量用药史。绝大多数（n = 86,92%）的参与者想知道他们在使用药物之前是否有芬太尼。65名（70%）参与者报告担心他们的药物被芬太尼污染。在简短的训练之后，几乎所有的参与者（n = 88,95%）都报告说他们计划使用试纸。超过90%的参与者报告说，他们愿意使用快速试纸，而不管是否吸毒过量，这表明快速芬太尼测试是罗德岛吸毒的年轻人可以接受的减少危害的干预措施。研究随访正在进行中，以确定参与者是否、如何以及在什么情况下使用快速试纸，以及阳性结果是否会导致过量风险行为的改变。
Synthetic opioid overdose mortality among young adults has risen more than 300% in the USA since 2013, primarily due to the contamination of heroin and other drugs with illicitly manufactured fentanyl. Rapid test strips, which can be used to detect the presence of fentanyl in drug samples (before use) or urine (after use), may help inform people about their exposure risk. The purpose of this study was to determine whether young adults who use drugs were willing to use rapid test strips as a harm reduction intervention to prevent overdose. We hypothesized that those who had ever overdosed would be more willing to use the test strips. We recruited a convenience sample of young adults who use drugs in Rhode Island from May to September 2017. Eligible participants (aged 18 to 35 with past 30-day drug use) completed an interviewer-administered survey. The survey assessed participant’s socio-demographic and behavioral characteristics, overdose risk, as well as suspected fentanyl exposure, and willingness to use take-home rapid test strips to detect fentanyl contamination in drugs or urine. Participants were then trained to use the test strips and were given ten to take home. Among 93 eligible participants, the mean age was 27 years (SD = 4.8), 56% (n = 52) of participants were male, and 56% (n = 52) were white. Over one third (n = 34, 37%) had a prior overdose. The vast majority (n = 86, 92%) of participants wanted to know if there was fentanyl in their drug supply prior to their use. Sixty-five (70%) participants reported concern that their drugs were contaminated with fentanyl. After the brief training, nearly all participants (n = 88, 95%) reported that they planned to use the test strips. More than 90% of participants reported willingness to use rapid test strips regardless of having ever overdosed, suggesting that rapid fentanyl testing is an acceptable harm reduction intervention among young people who use drugs in Rhode Island. Study follow-up is ongoing to determine whether, how, and under what circumstances participants used the rapid test strips and if a positive result contributed to changes in overdose risk behavior.
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影响因子：
4.4
作者：
Amlani A;McKee G;Khamis N;Raghukumar G;Tsang E;Buxton JA
通讯作者：
Buxton JA
影响因子：
4.2
作者：
Caudarella, Alexander;Dong, Huiru;Hayashi, Kanna
通讯作者：
Hayashi, Kanna
影响因子：
33.9
作者：
Gladden, R. Matthew;Martinez, Pedro;Seth, Puja
通讯作者：
Seth, Puja
DOI：
10.15585/mmwr.ss6619a1
发表时间：
2017-10-20
期刊：
Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002)
影响因子：
--
作者：
Mack KA;Jones CM;Ballesteros MF
通讯作者：
Ballesteros MF
高风险年轻人使用艾滋病毒自我测试的信息，动机和行为技巧。
影响因子：
4.4
作者：
Brown W 3rd;Carballo-Diéguez A;John RM;Schnall R
通讯作者：
Schnall R