AN ANTIBIOTIC FROM TRICHODERMA-KONINGII ACTIVE AGAINST SOILBORNE PLANT-PATHOGENS
AN ANTIBIOTIC FROM TRICHODERMA-KONINGII ACTIVE AGAINST SOILBORNE PLANT-PATHOGENS
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DOI：
10.1021/np50061a008
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发表时间：
1989-01-01
影响因子：
5.1
通讯作者：
GHISALBERTI, EL
中科院分区：
文献类型：
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作者：
DUNLOP, RW;SIMON, A;GHISALBERTI, EL
从土壤中分离的科宁木霉在纯培养中产生的主要代谢物是一种新的抗生素，它能抑制全蚀性真菌谷粒革霉菌（Gaeumannomyces graminis vars tritici）的腐生生长。化合物4,8-二羟基-2-（1-羟基庚基）-3,4,5,6,7,8-六氢- 2h -1-苯并吡喃-5- 1[2]的结构通过光谱方法推导，并允许相对立体化学（2S*, 4R*, 8R*, 1' S*）分配。该化合物和含该化合物的肉汤培养物在体外抑制全蚀菌的生长。在琼脂培养中产生的化合物抑制了其他几种土传植物病原体的生长。
A new antibiotic has been obtained as the major metabolite produced in pure culture by Trichoderma koningii isolated from soil suppressive to the saprophytic growth of the take-all fungus, Gaeumannomyces graminis var. tritici. The structure of the compound, 4,8-dihydroxy-2-(1-hydroxyheptyl)-3,4,5,6,7,8-hexahydro-2H-1-benzopyran-5-one [2], has been deduced by spectroscopic methods that also allow the relative stereochemistry (2S*, 4R*, 8R*, 1''S*) to be assigned. The compound and broth culture containing the compound inhibited the growth of the take-all fungus in vitro. The compound produced in agar culture inhibited the growth of several other soilborne plant pathogens.