Comparison of intensity based similarity measures for matching genomic structures in microscopic images of living cells.
Comparison of intensity based similarity measures for matching genomic structures in microscopic images of living cells.
复制标题
用于匹配活细胞显微图像中基因组结构的基于强度的相似性测量的比较。
DOI：
10.1109/iembs.2006.260165
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Berezney,Ronald
中科院分区：
文献类型：
--
作者：
Bhattacharya,Sambit;Acharya,Raj;Pliss,Artem;Malyavantham,KishoreS;Berezney,Ronald
This paper presents our comparative study of the application of intensity based similarity measures to the problem of matching genomic structures in microscopic images of living cells. As part of our ongoing research, we present here for the first time evidence from experiments and simulations that show the benefit of using an iterative matching algorithm guided by an intensity based similarity measure. Our experimental results are compared against a gold standard and suggest the measures that work best in the presence of fluorescent decay and other problems inherent to time-lapse microscopy. This makes our approach widely applicable in the study of the dynamics of living cells with time-lapse microscopic imaging
