Physical activity is inversely associated with multimorbidity in elderly men: Results from the KORA-Age Augsburg Study
Physical activity is inversely associated with multimorbidity in elderly men: Results from the KORA-Age Augsburg Study
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DOI：
10.1016/j.ypmed.2013.02.014
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发表时间：
2013-07-01
影响因子：
5.1
通讯作者：
Thorand, Barbara
中科院分区：
文献类型：
--
作者：
Autenrieth, Christine S.;Kirchberger, Inge;Thorand, Barbara
Objective.体育活动被认为在预防几种慢性疾病方面发挥着关键作用。然而，关于体力活动和多发性硬化症之间的关联的数据缺乏。使用2008/09年在奥格斯堡/德国和两个相邻县进行的基于人群的KORA（奥格斯堡地区合作健康研究）-年龄项目的1007名65-94岁男性和女性的数据，确定了13种慢性疾病，并根据老年人自我报告体力活动量表（PASE）计算体力活动评分。采用多变量性别特异性logistic回归分析确定持续体力活动评分与多发病（13种疾病中>= 2种）的相关性。男性的体力活动（平均PASE评分+/- SD）（125.1 +/- 59.2）高于女性（112.2 +/- 492）。在男性中，PASE评分每增加1个标准差，多发病的比值比（OR）为0.73（95%CI：0.60-0.90）。在女性中未观察到显著性结果（OR：1.05，95%CI：0.83-133）。我们证明了体力活动与男性多发性硬化症之间的负相关。进一步的前瞻性研究必须证实效应的时间性。(C)2013 Elsevier Inc. All rights reserved.
Objective. Physical activity is suggested to play a key role in the prevention of several chronic diseases. However, data on the association between physical activity and multimorbidity are lacking.Methods. Using data from 1007 men and women aged 65-94 years who participated in the population-based KORA (Cooperative Health Research in the Region of Augsburg)-Age project conducted in Augsburg/Germany and two adjacent counties in 2008/09, 13 chronic conditions were identified, and physical activity scores were calculated based on the self-reported physical activity scale for the elderly (PASE). Multivariable sex-specific logistic regression was applied to determine the association of the continuous physical activity score with multimorbidity (>= 2 out of 13 diseases).Results. Physical activity (mean PASE score +/- SD) was higher in men (125.1 +/- 59.2) than in women (112.2 +/- 492). Among men, the odds ratio (OR) for multimorbidity was 0.73 (95% CI: 0.60-0.90) for a 1 standard deviation increase of the PASE score. No significant results could be observed for women (OR: 1.05; 95% CI: 0.83-133).Conclusion. We demonstrated an inverse association between physical activity and multimorbidity among men. Further prospective studies have to confirm the temporality of effects. (C) 2013 Elsevier Inc. All rights reserved.