Predictors of cognitive appraisals following genetic testing for BRCA1 and BRCA2 mutations
Predictors of cognitive appraisals following genetic testing for BRCA1 and BRCA2 mutations
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DOI：
10.1023/b:jobm.0000042411.56032.42
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发表时间：
2004-08-01
影响因子：
3.1
通讯作者：
Lerman, C
中科院分区：
文献类型：
--
作者：
Halbert, CH;Schwartz, MD;Lerman, C
The objectives of this study were (1) to describe perceptions of stress and confidence following genetic testing for BRCA1 and BRCA2 (BRCA1/2) mutations and (2) to identify predictors of these processes. Participants were 130 high-risk women affected with cancer who received BRCA1/2 test results. Individual difference characteristics and interpersonal factors were measured by self-report before genetic counseling and perceptions of stress and confidence were evaluated by self-report 1 month following disclosure of test results. BRCA1/2 test results had a significant effect only on perceptions of stress (beta = 0.38, p = 0.0001), while trait anxiety had a significant effect on both perceptions of stress (beta = 0.44, p = 0.0001) and confidence (beta = - 0.41, p = 0.001). These results suggest that interventions designed to address perceptions of stress related to medical decision-making and familial concerns may need to be targeted to BRCA1/2 mutation carriers and individuals who are highly anxious.
