Dual-energy lung perfusion and ventilation CT in children
Dual-energy lung perfusion and ventilation CT in children
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DOI：
10.1007/s00247-012-2465-4
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发表时间：
2013-03-01
影响因子：
2.3
通讯作者：
Goo, Hyun Woo
中科院分区：
文献类型：
--
作者：
Goo, Hyun Woo
双能量胸部CT提供了两个关键的肺部生理信息，即区域灌注和换气，自从双源CT问世以来，一直被积极研究以寻找临床相关的应用。双能量胸部CT提供的这种功能信息是补充的，因为双能量胸部CT完全保留了高分辨率的胸部解剖。此外，虚拟非对比成像可以省略对比度前扫描。在这方面，双能量CT成像技术至少是剂量中性的，这是儿科成像的关键要求。本文就双能胸部CT评价儿童肺血流灌注和换气的成像方案、分析方法、临床应用和诊断缺陷作一综述。
Dual-energy thoracic CT provides two key insights into lung physiology, i.e. regional perfusion and ventilation, and has been actively investigated to find clinically relevant applications since the introduction of dual-source CT. This functional information provided by dual-energy thoracic CT is supplementary because high-resolution thoracic anatomy is entirely preserved on dual-energy thoracic CT. In addition, virtual non-contrast imaging can omit pre-contrast scanning. In this respect, dual-energy CT imaging technique is at least dose-neutral, which is a critical requirement for paediatric imaging. In this review, imaging protocols, analysis methods, clinical applications and diagnostic pitfalls of dual-energy thoracic CT for evaluating lung perfusion and ventilation in children are described.