Human attachment security is mediated by the amygdala: Evidence from combined fMRI and psychophysiological measures
Human attachment security is mediated by the amygdala: Evidence from combined fMRI and psychophysiological measures
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DOI：
10.1002/hbm.20206
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发表时间：
2006-08-01
影响因子：
4.8
通讯作者：
Phillips, Mary L.
中科院分区：
文献类型：
--
作者：
Lemche, Erwin;Giampietro, Vincent P.;Phillips, Mary L.
人类依恋安全性的神经基础尚未得到研究。使用事件相关的功能磁共振成像（NRI）和皮肤电导水平的同时记录，我们测量了神经和自主神经反应在健康的成年人在语义概念启动任务测量人类附件安全“代理”。表现在压力，但不是一个中性的总理条件与双边杏仁核的反应。此外，双侧杏仁核内的活动水平高度正相关的依恋不安全感和自主神经反应在压力启动条件。因此，我们证明了杏仁核在介导与人类依恋不安全感相关的自主活动中的关键作用。
The neural basis of human attachment security remains unexamined. Using event-related functional magnetic resonance imaging (NRI) and simultaneous recordings of skin conductance levels, we measured neural and autonomic responses in healthy adult individuals during a semantic conceptual priming task measuring human attachment security "by proxy". Performance during a stress but not a neutral prime condition was associated with response in bilateral amygdalae. Furthermore, levels of activity within bilateral amygdalae were highly positively correlated with attachment insecurity and autonomic response during the stress prime condition. We thereby demonstrate a key role of the amygdala in mediating autonomic activity associated with human attachment insecurity.