A new solution to the curved Ewald sphere problem for 3D image reconstruction in electron microscopy
A new solution to the curved Ewald sphere problem for 3D image reconstruction in electron microscopy
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DOI：
10.1016/j.ultramic.2021.113234
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发表时间：
2021-02-27
期刊：
影响因子：
2.2
通讯作者：
Kirian, R. A.
中科院分区：
文献类型：
--
作者：
Chen, J. P. J.;Schmidt, K. E.;Kirian, R. A.
我们开发了一种算法，能够成像的三维对象给定的集合的二维图像的对象，显着影响的埃瓦尔德球的曲率。这些二维图像不能近似为对象的投影。这样的算法在冷冻电子显微镜中是有用的，其中需要更大的样品、更高的分辨率或更低能量的电子束，所有这些都有助于埃瓦尔德曲率的意义。
We develop an algorithm capable of imaging a three-dimensional object given a collection of two-dimensional images of that object that are significantly influenced by the curvature of the Ewald sphere. These two-dimensional images cannot be approximated as projections of the object. Such an algorithm is useful in cryoelectron microscopy where larger samples, higher resolution, or lower energy electron beams are desired, all of which contribute to the significance of Ewald curvature.