Pathology of Takayasu arteritis: A brief review.
Pathology of Takayasu arteritis: A brief review.
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DOI：
10.4103/0974-2069.107235
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发表时间：
2013-01
影响因子：
0.7
通讯作者：
Deshpande JR
中科院分区：
文献类型：
--
作者：
Vaideeswar P;Deshpande JR
多发性大动脉炎（TA）是一种慢性特发性肉芽肿性血管炎，主要表现为胰腺炎.自身免疫细胞介导的免疫可能是该疾病的原因。炎症从外膜开始并进展到内膜，导致成人和儿童节段性狭窄、闭塞、扩张和/或动脉瘤形成。本文就其发病机制、成人和儿童的病理和临床特点作一综述。
Takayasu arteritis (TA) is a chronic idiopathic and granulomatous vasculitis, manifesting mainly as a panaortitis. Autoimmune cell-mediated immunity is probably responsible for the disease. The inflammation commences from the adventitia and progresses to the intima and leads to, both in adults and children, segmental stenosis, occlusion, dilatation, and/or aneurysm formation. This review focuses briefly on the etiopathogenesis, and describes the pathological and clinical features in adults and children.