Blood gas values in clamped and unclamped umbilical cord at birth
Blood gas values in clamped and unclamped umbilical cord at birth
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DOI：
10.1016/j.earlhumdev.2014.03.010
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发表时间：
2014-09-01
影响因子：
2.5
通讯作者：
Dani, Carlo
中科院分区：
文献类型：
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作者：
Di Tommaso, Mariarosaria;Seravalli, Viola;Dani, Carlo
目的：为了确定的可靠性的脐带血气体分析的unclamped脐带相比，标准技术的采样对双clamped cord.Study设计：前瞻性观察研究进行了46个单胎新生儿阴道分娩的条款。在出生后90 s内从未夹持的脐带中采集配对的脐动脉和静脉血样，并在夹持后从同一脐带中采集配对的脐动脉和静脉血样，在第一次采血后立即进行夹持。结果测量：动脉和静脉血分析pH、PO2、pCO（2）、SaO（2）、血红蛋白浓度（ctHb）和碱过剩（BE）。结果：两组间动脉血pH、PO2、pCO（2）、SaO（2）、ctHb值无显著性差异（P> 0.05）。唯一的显著差异与BE有关（p < 0.001）。静脉血pH值、PO2、pCO2值在脐带钳夹前后无显著性差异，SaO2、ctHb、BE值在脐带钳夹前后有显著性差异（p < 0.05）。结论：脐带钳夹前后动脉血气指标及主要静脉血气指标无显著性差异。在出生后立即对未夹紧的脐带进行脐带血气体分析采样，而不会降低分析的准确性。(C)2014爱思唯尔爱尔兰有限公司版权所有。
Aim: To determine the reliability of the cord blood gas analysis on the unclamped cord compared to the standard technique of sampling on double clamped cord.Study design: Prospective observational study conducted on 46 singleton neonates vaginally delivered at term. Matched pairs of umbilical artery and vein blood samples were collected from undamped cord within 90 s after birth and from the same cord after clamping, with the clamping occurring immediately after the first blood collection. A blood gas analysis was performed on each collected sample.Outcome measures: Arterial and venous blood samples were analyzed for pH, PO2, pCO(2), SaO(2), hemoglobin concentration (ctHb) and base excess (BE). The values were compared between the two groups (clamped vs unclamped) using a Wilcoxon test.Results: No significant difference was found in pH, PO2, pCO(2), SaO(2) and ctHb values on arterial blood between unclamped and clamped cord. The only significant difference was related to BE (p < 0.001). For the venous blood, the values of pH, PO2, pCO(2) were comparable between unclamped and clamped cord, while the values of SaO(2), ctHb and BE were significantly different (p < 0.05).Conclusion: No significant difference was found in almost all the arterial blood gas parameters and in the main venous blood gas parameters between unclamped and clamped cord. Sampling of cord blood for gas analysis may be performed on the unclamped cord right after birth without reducing the accuracy of the analysis. (C) 2014 Elsevier Ireland Ltd. All rights reserved.