Tea intake is inversely related to blood pressure in older women
Tea intake is inversely related to blood pressure in older women
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DOI：
10.1093/jn/133.9.2883
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发表时间：
2003-09-01
影响因子：
4.2
通讯作者：
Prince, RL
中科院分区：
文献类型：
--
作者：
Hodgson, JM;Devine, A;Prince, RL
茶富含多酚，其具有降低血压的活性。长期定期喝茶对血压的影响仍不确定。我们对 218 名 70 岁以上女性进行了横断面研究，调查了茶摄入量和茶多酚（4-O-甲基没食子酸）暴露的生物标志物与血压的关系。测量临床血压并使用 24 小时饮食回忆评估茶摄入量；同一时间段的 24 小时尿液样本中检测了 4-0-甲基没食子酸。平均 (95% Cl) 每日茶摄入量为 525 (475, 600) mL。平均收缩压和舒张压分别为 138.1 (135.6, 140.6) 和 73.5 (72.1, 74.9) mm Hg。较高的茶摄入量和较高的 4-O-甲基没食子酸排泄量与显着降低的收缩压（分别为 P = 0.002 和 P = 0.040）和舒张压（分别为 P = 0.027 和 P < 0.001）相关。茶摄入量增加 250 mL/d（1 杯）与收缩压降低 2.2（0.8,3.6）毫米汞柱和舒张压降低 0.9（0.1,1.7）毫米汞柱相关。观察到的茶摄入量和 4-O-甲基没食子酸之间的关联与长期定期喝茶可能对老年女性血压产生有利影响的假设是一致的。
Tea is rich in polyphenols, which have activities consistent with blood pressure-lowering potential. The effects of long-term regular ingestion of tea on blood pressure remain uncertain. We investigated the relationships of tea intake and a biomarker of exposure to tea-derived polyphenols (4-O-methylgallic acid) with blood pressure in a cross-sectional study of 218 women > 70 y old. Clinic blood pressures were measured and tea intake was assessed using a 24-h dietary recall; 4-0-methylgallic acid was measured for the same period in a 24-h urine sample. Mean (95% Cl) daily tea intake was 525 (475, 600) mL. Mean systolic and diastolic blood pressures were 138.1 (135.6, 140.6) and 73.5 (72.1, 74.9) mm Hg. Higher tea intake and higher 4-O-methylgallic acid excretion were associated with significantly lower systolic (P = 0.002 and P = 0.040, respectively) and diastolic (P = 0.027 and P < 0.001, respectively) blood pressures. A 250 mL/d (1 cup) increase in tea intake was associated with a 2.2 (0.8,3.6) mm Hg lower systolic blood pressure and a 0.9 (0.1, 1.7) mm Hg lower diastolic blood pressure. The observed associations for both tea intake and 4-O-methylgallic acid are consistent with the hypothesis that long-term regular ingestion of tea may have a favorable effect on blood pressure in older women.