Hepatitis viruses: changing patterns of human disease.
Hepatitis viruses: changing patterns of human disease.
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肝炎病毒：改变人类疾病的模式。
DOI：
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发表时间：
1994
影响因子：
11.1
通讯作者：
R. Purcell
中科院分区：
文献类型：
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作者：
R. Purcell
病毒性肝炎是一种古老的疾病，但直到20世纪40年代才认识到有一种以上的病原体，当时认为两种病毒（甲型肝炎病毒和B型肝炎病毒）是所有疾病的原因。在过去的20年里，又发现了三种肝炎病原体（丙型肝炎病毒、丁型肝炎病毒和戊型肝炎病毒），并且有证据表明至少还有一种病毒。五种公认的肝炎病毒中的每一种都属于不同的病毒家族，每一种都有独特的流行病学。这些病毒对社会的医学影响受到人类生态变化的强烈影响。这在某些情况下导致疾病减少，而在另一些情况下导致发病率增加。
Viral hepatitis is a disease of antiquity, but evidence for more than one etiologic agent has been recognized only since the 1940s, when two viruses (hepatitis A virus and hepatitis B virus) were thought to account for all disease. In the past 20 years, three additional hepatitis agents (hepatitis C virus, hepatitis D virus, and hepatitis E virus) have been discovered, and there is evidence for at least one additional virus. Each of the five recognized hepatitis viruses belongs to a different virus family, and each has a unique epidemiology. The medical impact of these viruses on society has been strongly influenced by changes in human ecology. This has resulted in some cases in diminished disease and in others in increases in the incidence of disease.