Comparative outcomes of adenosquamous carcinoma of the pancreas: An analysis of the National Cancer Database
Comparative outcomes of adenosquamous carcinoma of the pancreas: An analysis of the National Cancer Database
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DOI：
10.1002/jso.25112
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发表时间：
2018-07-01
影响因子：
2.5
通讯作者：
Yopp, Adam C.
中科院分区：
文献类型：
--
作者：
Hester, Caitlin A.;Augustine, Mathew M.;Yopp, Adam C.
背景资料：胰腺腺鳞癌（ASCP）是一种与胰腺腺癌（PDAC）不同的组织学类型，关于其自然史和结局指标的数据很少。本研究的目的是描述ASCP的临床病理特征，在一个大的患者队列中比较手术切除患者PDAC.Methods的结局指标：我们确定了2004年至2012年国家癌症数据库诊断为ASCP或PDAC的患者。患者的人口统计学，肿瘤特征，治疗方案，和总生存率进行了分析groups.Results：我们确定了207073例患者：205328（99%）在PDAC组和1745（1%）在ASCP组。ASCP肿瘤较大，更常位于体/尾部位（36% vs 24%，P
Background: A paucity of data exists regarding the natural history and outcome measures of adenosquamous carcinoma of the pancreas (ASCP), a histology distinct from pancreatic adenocarcinoma (PDAC). The aim of this study is to characterize the clinicopathological features of ASCP in a large cohort of patients comparing outcome measures of surgically resected patients to PDAC.Methods: We identified patients diagnosed with ASCP or PDAC from the National Cancer Database from 2004 to 2012. Patient demographics, tumor characteristics, treatment regimens, and overall survival were analyzed between the groups.Results: We identified 207073 patients: 205328 (99%) in the PDAC group and 1745 (1%) in the ASCP group. ASCP tumors were larger, located more frequently in a body/tail location (36% vs 24%, P