A multiscale bidirectional coupling framework.
A multiscale bidirectional coupling framework.
复制标题
多尺度双向耦合框架。
DOI：
10.1109/iembs.2011.6090672
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Einstein,DanielR
中科院分区：
文献类型：
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作者：
Kabilan,Senthil;Kuprat,AndrewP;Hlastala,MichaelP;Corley,RichardA;Einstein,DanielR
肺在从气管到肺泡的多个尺度上呈几何连接。一个主要的计算挑战是使用尺度之间的迭代通信将描述较低尺度的ode与气道力学的3D有限元或有限体积模型紧密联系起来。在这项研究中，我们开发了一个新的多尺度计算框架，用于双向耦合3D CFD模型和低阶ode系统。为了验证耦合框架，构建了第4代和第8代Weibel肺模型。对于耦合CFD-ODE模拟，肺模型在不同代被截断，RL电路代表截断的部分。将耦合模型的流动特性与未截断的全3D CFD模型在吸气和呼气峰值时的流动特性进行了比较。结果表明，在任何时间或模拟中，未耦合模型与耦合模型在给定位置上的质量通量和/或压力差均不大于2.43%。耦合模型与非耦合模型在主要位置的流动特性具有较好的一致性。值得注意的是，由于Krylov子空间的重用，ODE耦合的成本并不比具有简单规定出口压力值的不耦合全3D-CFD计算大多少。
The lung is geometrically articulated across multiple scales from the trachea to the alveoli. A major computational challenge is to tightly link ODEs that describe lower scales to 3D finite element or finite volume models of airway mechanics using iterative communication between scales. In this study, we developed a novel multiscale computational framework for bidirectionally coupling 3D CFD models and systems of lower order ODEs. To validate the coupling framework, a four and eight generation Weibel lung model was constructed. For the coupled CFD-ODE simulations, the lung models were truncated at different generations and a RL circuit represented the truncated portion. The flow characteristics from the coupled models were compared to untruncated full 3D CFD models at peak inhalation and peak exhalation. Results showed that at no time or simulation was the difference in mass flux and/or pressure at a given location between uncoupled and coupled models was greater than 2.43%. The flow characteristics at prime locations for the coupled models showed good agreement to uncoupled models. Remarkably, due to reuse of the Krylov subspace, the cost of the ODE coupling is not much greater than uncoupled full 3D-CFD computations with simple prescribed pressure values at the outlets.