Parallelization of microfluidic flow-focusing devices
Parallelization of microfluidic flow-focusing devices
复制标题
DOI：
10.1103/physreve.95.043105
复制
发表时间：
2017-04-14
影响因子：
2.4
通讯作者：
Weitz, David A.
中科院分区：
文献类型：
--
作者：
Amstad, Esther;Chen, Xiaoming;Weitz, David A.
微流体聚焦装置提供了对流体流动的出色控制，使液滴的形成具有狭窄的尺寸分布。然而，微流控聚焦装置的吞吐量是有限的，并且通过并行运行多个液滴制造器来扩大规模往往会损害其运行的鲁棒性。我们证明，如果从与内相相反的方向注入外相，则会促进并行化，因为流体注入流速（液滴形成从挤压状态转变为滴下状态）向更高的值偏移。
Microfluidic flow-focusing devices offer excellent control over fluid flow, enabling formation of drops with a narrow size distribution. However, the throughput of microfluidic flow-focusing devices is limited and scale-up through operation of multiple drop makers in parallel often compromises the robustness of their operation. We demonstrate that parallelization is facilitated if the outer phase is injected from the direction opposite to that of the inner phase, because the fluid injection flow rate, where the drop formation transitions from the squeezing into the dripping regime, is shifted towards higher values.