Quantitative relations between the eyeball, the optic nerve, and the optic canal important for intracranial pressure monitoring
Quantitative relations between the eyeball, the optic nerve, and the optic canal important for intracranial pressure monitoring
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DOI：
10.1186/1746-160x-10-32
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发表时间：
2014-08-17
影响因子：
3
通讯作者：
Bekerman, Inessa
中科院分区：
文献类型：
--
作者：
Vaiman, Michael;Gottlieb, Paul;Bekerman, Inessa
目的：为了找到视神经鞘（ONSD）的直径之间的相关性，眼球，和视神经管，可能是重要的颅内压monitoring.Methods：在前瞻性队列研究中，连续400例（18+）健康的眼睛和视神经和神经系统疾病的情况下的CT数据收集和分析。在获得CT扫描时，测量视神经鞘、眼球和视神经管的直径并进行统计学分析。比较从左右眼球和视神经获得的数据。结果：正常人眶内不同部位的ONSD在3.65 ~ 5.17mm之间，性别和年龄组间差异无统计学意义。眼球横径（ETD）与ONSD之间有很强的相关性，可以表示为ONSD/ETD指数。在健康人中，ONSD/ETD指数为0.19。结论：ONSD除以眼球ETD计算的指数为ONSD颅内压测量技术提供了精确的标准数据。当测量ONSD用于颅内压监测时，如果在距离地球仪10 mm处测量直径，则可以获得最稳定的结果。这些数据可能作为一个规范的数据库，在急诊科和一般的神经实践。
Objective: To find correlations between diameters of the optic nerve sheath (ONSD), the eyeball, and the optic canal that might be important for intracranial pressure monitoring.Methods: In a prospective cohort study, the CT data of consecutive 400 adults (18+) with healthy eyes and optic nerves and absence of neurological diseases were collected and analyzed. When the CT scans were obtained, the diameters of the optic nerve sheath, the eyeball, and the optic canal were measured and statistically analyzed. The data obtained from the left and from the right eyeballs and optic nerves were compared. The correlation analysis was performed within these variables, with the gender, and the age.Results: In healthy persons, the ONSD varies from 3.65 mm to 5.17 mm in different locations within the intraorbital space with no significant difference between sexes and age groups. There is a strong correlation between the eyeball transverse diameter (ETD) and ONSD that can be presented as ONSD/ETD index. In healthy subjects, the ONSD/ETD index equals 0.19.Conclusion: The calculation of an index when ONSD is divided by the ETD of the eyeball presents precise normative database for ONSD intracranial pressure measurement technique. When the ONSD is measured for intracranial pressure monitoring, the most stable results can be obtained if the diameter is measured 10 mm from the globe. These data might serve as a normative database at emergency departments and in general neurological practice.