SPATIAL-RESOLUTION OF NEUROMAGNETIC RECORDS - THEORETICAL CALCULATIONS IN A SPHERICAL MODEL
SPATIAL-RESOLUTION OF NEUROMAGNETIC RECORDS - THEORETICAL CALCULATIONS IN A SPHERICAL MODEL
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DOI：
10.1016/0168-5597(88)90020-2
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发表时间：
1988-01-01
期刊：
影响因子：
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通讯作者：
SARVAS, J
中科院分区：
文献类型：
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作者：
HARI, R;JOUTSINIEMI, SL;SARVAS, J
采用球形导体模型对脑磁图（MEG）的空间分辨率进行了计算机模拟研究。通过计算三维源位置的置信限，得到了偶极子绝对位置的精度。确定两个源的相对位置的准确性是通过计算可以检测到的具有统计学意义的源位置的最小偏移来估计的。结果被用来说明空间分辨率的依赖性的几个因素，包括噪声，源深度，源强度，磁通Transformer配置和测量位置的选择。在最佳条件下，可以检测到表面非同时源中几毫米的分离，而对于更深的源，分辨率更差。
Spatial resolution of magnetoencephalography (MEG) was studied by computer simulations using a spherical conductor model for the head. The accuracy obtainable in the absolute location of a dipole was found by calculating the confidence limits for source location in 3 dimensions. The accuracy in determining the relative locations of two sources was estimated by calculating the smallest shift in source location that could be detected with statistical significance. The results were used to illustrate the dependence of spatial resolution on several factors including noise, source depth, source strength, flux transformer configuration and the choice of the measurement locations. Under optimal conditions, separations of a couple of millimeters in superficial non-simultaneous sources can be detected, whereas for deeper sources the resolution is worse.