Factors that influence magnetic orientation in Caenorhabditis elegans
Factors that influence magnetic orientation in Caenorhabditis elegans
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DOI：
10.1007/s00359-019-01364-y
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发表时间：
2020-05-01
影响因子：
2.1
通讯作者：
Vidal-Gadea, A. G.
中科院分区：
文献类型：
--
作者：
Bainbridge, C.;Clites, B. L.;Vidal-Gadea, A. G.
感应磁场的动物会根据时间、空间和环境因素（如季节、气候和在地磁场中的位置）的不同，以不同角度定位地球磁场。磁性迁移偏好如何随内部或外部刺激而改变尚不清楚。我们以前发现秀丽隐杆线虫倾向于两个相反方向之一的磁场迁移。在这里，我们展示了来自我们实验室的新数据，以及一个独立实验室的复制，以测试时间、空间和环境因素如何影响蠕虫在趋磁过程中形成的独特时空轨迹。我们发现，在90分钟的实验过程中，蠕虫逐渐改变了它们的平均偏好取向角，与磁场的角度变化了约180度。此外，我们发现野生型N2菌株更倾向于朝向朝北的圆盘状磁铁的左侧。最后，与线虫的其他行为类似，我们发现在干燥条件下（< 50% RH），磁性取向可能更加稳健。我们的发现有助于解释为什么秀丽隐杆线虫在不同时期和不同形状的磁场中以不同的模式积累。这些结果为研究状态依赖磁取向的行为遗传基础提供了一个易于处理的系统。
Magnetoreceptive animals orient to the earth's magnetic field at angles that change depending on temporal, spatial, and environmental factors such as season, climate, and position within the geomagnetic field. How magnetic migratory preference changes in response to internal or external stimuli is not understood. We previously found that Caenorhabditis elegans orients to magnetic fields favoring migrations in one of two opposite directions. Here we present new data from our labs together with replication by an independent lab to test how temporal, spatial, and environmental factors influence the unique spatiotemporal trajectory that worms make during magnetotaxis. We found that worms gradually change their average preferred angle of orientation by ~ 180 degrees to the magnetic field during the course of a 90-min assay. Moreover, we found that the wild-type N2 strain prefers to orient towards the left side of a north-facing up, disc-shaped magnet. Lastly, similar to some other behaviors in C. elegans, we found that magnetic orientation may be more robust in dry conditions (< 50% RH). Our findings help explain why C. elegans accumulates with distinct patterns during different periods and in differently shaped magnetic fields. These results provide a tractable system to investigate the behavioral genetic basis of state-dependent magnetic orientation.