Which malaria rapid test for Madagascar?: Field and laboratory evaluation of three tests and expert microscopy of samples from suspected malaria patients in Madagascar
Which malaria rapid test for Madagascar?: Field and laboratory evaluation of three tests and expert microscopy of samples from suspected malaria patients in Madagascar
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DOI：
10.4269/ajtmh.2007.76.481
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发表时间：
2007-03-01
影响因子：
3.3
通讯作者：
Menard, Didier
中科院分区：
文献类型：
--
作者：
Ratsimbasoa, Arsene;Randriamanantena, Arthur;Menard, Didier
2005年10月和11月进行了实地和实验室研究，对三种疟疾快速检测方法的性能进行了比较评价，其中两种方法是最近引进的（CareStart（TM）疟疾检测方法和SD疟疾抗原Bioline（TM）检测方法），另一种方法是众所周知的OptiMAL-IT（TM）检测方法。与显微镜相比，三种检测方法检测恶性疟原虫疟疾的灵敏度分别为CareStart（TM）疟疾检测法97%、SD疟疾抗原Bioline（TM）检测法89.4%和OptiMAL-IT（TM）检测法92.6%。这三种检测方法在检测非恶性疟原虫感染时的敏感性较低，在寄生虫血症水平时敏感性降低
Field and laboratory studies were carried out in October and November 2005 to provide a comparative evaluation of the performance of three rapid malaria detection tests, two of which were recently introduced (the CareStart (TM) Malaria test and the SD Malaria Antigen Bioline (TM) test) and the well-known OptiMAL-IT (TM) test. Compared with microscopy, the sensitivity of the three tests to detect Plasmodium falciparum malaria was 97% for the CareStart (TM) Malaria test, 89.4% for the SD Malaria Antigen Bioline (TM) test, and 92.6% for the OptiMAL-IT (TM) test. The three tests were less sensitive in detecting non-P. falciparum infections, and the sensitivity decreased at levels of parasitemia